Celiac disease and COVID-19 pandemic: should we worry?

Y Gokden1, S Hot2, M Adas3

  • 1Department of Gastroenterology, University of Health Sciences Cemil Tascioglu City Hospital, Istanbul, Turkey.

Insights

Celiac disease patients on a gluten-free diet face no increased risk of COVID-19 infection and experience a similar clinical course. Anxiety levels were mild, though access to gluten-free products decreased during the pandemic.

Area of Science:

  • Immunology
  • Gastroenterology
  • Epidemiology

Background:

  • The COVID-19 pandemic heightened concerns for individuals with chronic conditions, including Celiac disease (CD).
  • Understanding COVID-19's impact on CD patients is crucial for managing their health during outbreaks.
  • This study investigated COVID-19 infection rates, clinical outcomes, and psychological effects in CD patients.

Purpose of the Study:

  • To assess the frequency and clinical course of COVID-19 in Celiac disease patients.
  • To examine gluten-free product (GFP) purchasing adherence and dietary compliance during the pandemic.
  • To evaluate the influence of anxiety on CD symptoms amidst the COVID-19 outbreak.

Main Methods:

  • A questionnaire assessed GFP availability and dietary adherence via phone and email.
  • The State-trait Anxiety Inventory (STAI) measured anxiety levels.
  • COVID-19 diagnosis and clinical outcomes were recorded for CD patients.

Main Results:

  • One hundred and one CD patients participated.
  • A significant decrease in GFP availability was reported during the pandemic.
  • Mild anxiety was prevalent (State: 40.7±7.9, Trait: 44.5±8.5); two patients contracted COVID-19.

Conclusions:

  • Celiac disease patients on a gluten-free diet do not exhibit increased susceptibility to COVID-19.
  • The clinical course of COVID-19 in CD patients is comparable to that of the general population.
  • Dietary adherence and anxiety management remain important considerations for CD patients during health crises.
Abstract

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