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Reductive TCA cycle metabolism fuels glutamine- and glucose-stimulated insulin secretion

Guo-Fang Zhang1, Mette V Jensen2, Sarah M Gray2

  • 1Sarah W. Stedman Nutrition and Metabolism Center and Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC 27701, USA; Department of Medicine, Endocrinology and Metabolism Division, Duke University Medical Center, Durham, NC 27701, USA.

Cell Metabolism
|December 15, 2020
PubMed

Keywords:
NADPHanaplerosisinsulin secretionisocitrate dehydrogenase-2metabolic fluxpancreatic islet β cellsreductive TCA cyclestable isotopes

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