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Cervical Pemphigus Vulgaris Presenting as Postmenopausal Bleeding.

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    |December 16, 2020
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    Pemphigus vulgaris, a blistering disease, can manifest as postmenopausal bleeding due to cervical involvement. Gynecologists and pathologists must recognize this rare presentation to avoid misdiagnosis and unnecessary procedures.

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    Area of Science:

    • Dermatology
    • Gynecology
    • Pathology

    Background:

    • Pemphigus vulgaris is a rare mucocutaneous blistering disease.
    • Genital involvement is uncommon, typically affecting the vulva and vagina.

    Observation:

    • Two cases of pemphigus vulgaris presented with postmenopausal bleeding.
    • Cervical involvement was identified as the source of bleeding in one case and suspected in the other.

    Findings:

    • Postmenopausal bleeding is an unreported symptom of pemphigus vulgaris.
    • Isolated cervical pemphigus vulgaris recurrence can mimic gynecological pathology.

    Implications:

    • Awareness of cervical pemphigus vulgaris is crucial for gynecologists and pathologists.
    • Timely diagnosis can prevent extensive work-ups and unnecessary interventions like hysterectomy.
    • Long-term survival in pemphigus patients increases the likelihood of such atypical presentations.