Related Experiment Video
Updated: Nov 25, 2025
A Web Tool for Generating High Quality Machine-readable Biological Pathways
Published on: February 8, 2017
PETAL: a Python tool for deep analysis of biological pathways
Giuseppe Sgroi1, Giulia Russo2, Francesco Pappalardo2
1Department of Mathematics and Computer Science, University of Catania, 95125 Catania, Italy.
Summary:
Although several bioinformatics tools have been developed to examine signaling pathways, little attention has been given to ever long-distance crosstalk mechanisms. Here, we developed PETAL, a Python tool that automatically explores and detects the most relevant nodes within a KEGG pathway, scanning and performing an in-depth search. PETAL can contribute to discovering novel therapeutic targets or biomarkers that are potentially hidden and not considered in the network under study.
Availabilityand Implementation:
PETAL is a freely available open-source software. It runs on all platforms that support Python3. The user manual and source code are accessible from https://github.com/Pex2892/PETAL.
