Related Experiment Video
Updated: Jul 21, 2026

Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss
Published on: January 25, 2016
Otological IgG4-Related Disease With Inner Ear Involvement: A Case Report and Review of Literature
Qinzhan Ren1, Jinfei Su1, Daoxing Zhang1
1Department of Otolaryngology-Head and Neck Surgery, 71044Xuanwu Hospital, Capital Medical University, Beijing, China.
Abstract:
Immunoglobulin G4-related disease (IgG4-RD) is a chronic inflammatory disease involving multiple organs. Some studies have reported otological manifestations of IgG4-RD, although most studies describe involvement of the middle ear, and reports on inner ear manifestations are limited. Here, we describe a case of a 30-year-old man with IgG4-RD involving the inner ear. This case demonstrated that IgG4-RD affected the inner ear and caused cochlear ossification. Cochlear implants may be considered for milder cases, and hormone and immunosuppressive therapy may control disease progression.
Related Concept Videos
The Cochlea
Glaucoma: Overview
Anatomy of the Ear
Equilibrium and Balance

