Related Experiment Video
Updated: Nov 25, 2025

RNA Pull-down Procedure to Identify RNA Targets of a Long Non-coding RNA
Published on: April 10, 2018
AnnoLnc: A One-Stop Portal to Systematically Annotate Novel Human Long Noncoding RNAs
De-Chang Yang1,2, Lan Ke1,2, Yang Ding1,2
1Biomedical Pioneering Innovation Center (BIOPIC), Beijing Advanced Innovation Center for Genomics (ICG), Center for Bioinformatics (CBI), Peking University, Beijing, China.
Abstract:
While more than a hundred thousand long noncoding RNAs (lncRNAs) have been identified in human genome, their biological functions and regulation are largely elusive. Here we present AnnoLnc, a one-stop online annotation portal for human lncRNAs ( http://annolnc1.gao-lab.org/ ). As the first (and the most comprehensive) Web server to provide on-the-fly annotation for novel human lncRNAs, AnnoLnc exploits more than 700 data sources to annotate inputted lncRNA systematically, spanning genomic location, secondary structure, expression patterns, coexpression-based functional annotation, transcriptional regulation, miRNA interaction, protein interaction, genetic association, and evolution. Moreover, in addition to a user-friendly Web interface, AnnoLnc can also be integrated into existing pipelines by either a set of JSON-based web service APIs or a stand-alone version for Linux server.
Related Concept Videos
lncRNA - Long Non-coding RNAs
lncRNA - Long Non-coding RNAs
RNA-seq
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while...
Genome Annotation and Assembly

