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Primary pulmonary diffuse large B-cell lymphoma with multiple ground-glass nodules as the primary manifestation: A
Qi Wang1, He Yan2, Rangrang Wang1
1Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Jilin University.
Introduction:
Primary pulmonary lymphoma (PPL) is a rare extranodal lymphoma. Only 5% to 20% of patients suffering from PPL have diffuse large β-cell lymphoma (DLBCL), and their chest computed tomography (CT) findings show single- or double-lung patchy or flocculated shadows, isolated or multifocal nodules, or masses. In this research paper, we report an older woman having multiple ground-glass nodules, who was eventually diagnosed with primary pulmonary diffuse large β-cell lymphoma (PPDLBCL).
Patient Concerns:
A 69-year-old woman suffering from cough was admitted to the Second Hospital of Jilin University.
Diagnoses:
A chest CT scan showed multiple ground-glass nodules. She had received 2 weeks of antibiotic treatment, but the multiple ground-glass nodules were still present. Lung biopsy was performed by tracheoscopy, which showed non-Hodgkin diffuse large β-cell lymphoma.
Interventions:
The patient received R-CHOP-21 chemotherapy.
Outcomes:
The multiple ground-glass nodules were absorbed.
Conclusion:
The current study shows that spotting multiple ground-glass nodules in the lungs is a clear indication of the presence of PPDLBCL. It is important to spread awareness of PPDLBCL, which needs timely diagnosis and management.
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