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Updated: Nov 25, 2025

08:04
In Vitro Tumor Cell Rechallenge For Predictive Evaluation of Chimeric Antigen Receptor T Cell Antitumor Function
Published on: February 27, 2019
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Predicting CAR-T cell Immunotherapy Success through ImmunoPET
Alessia Volpe1, Veronica L Nagle2, Jason S Lewis1,2,3
1Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
Abstract:
Chimeric antigen receptor (CAR)-T cell therapy has generated unprecedented advances in the treatment of hematologic cancers, but readily translatable imaging approaches to visualize the in vivo dynamics of CAR-T cells are lacking. Noninvasive PET imaging is the ideal tool to monitor CAR-T cells.See related article by Simonetta et al., p. 1058.

