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Cardiometabolic Risk in First Episode Psychosis Patients.

Jo Smith1, Lisa A Griffiths2, Marie Band3

  • 1School of Allied Health and Community, University of Worcester, Worcester, United Kingdom.

Frontiers in Endocrinology
|December 17, 2020
PubMed
Summary
This summary is machine-generated.

Young people with first episode psychosis exhibit high rates of cardiometabolic risk factors, including obesity and hypertension. Early physical health interventions are crucial to mitigate risks for cardiovascular disease in this population.

Keywords:
cardiometabolic riskduration of untreated psychosisfirst episode psychosislifestyle behaviorsmetabolic syndromeserious mental illness

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Area of Science:

  • Psychiatry
  • Cardiology
  • Public Health

Background:

  • Previous research indicates high metabolic syndrome prevalence and cardiovascular disease risk in European and USA schizophrenia patients.
  • Limited data exists on cardiometabolic risk factors at the onset of first episode psychosis.

Purpose of the Study:

  • To assess the prevalence of cardiometabolic risk factors in young individuals with first episode psychosis in the UK.
  • To identify clinical markers and health behaviors contributing to increased cardiovascular risk.

Main Methods:

  • Cross-sectional study of 46 participants with first episode psychosis (duration < 6 months).
  • Assessment included anthropometrics, blood pressure, heart rate, lipids, glycated hemoglobin, and health risk behaviors (smoking, diet, etc.).

Main Results:

  • High prevalence of elevated BMI (73%), abdominal adiposity (50%), hypertension (23%), and hypertriglyceridemia (40%).
  • Significant rates of smoking (55%), poor diet (52%), and sedentary behavior (29%) were self-reported.
  • Elevated resting heart rate (43%) and hypercholesterolemia (32%) were also observed.

Conclusions:

  • Young individuals with first episode psychosis present a significant cardiometabolic risk profile.
  • Integrated physical health interventions addressing clinical markers and lifestyle behaviors are essential early in treatment.