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Updated: Nov 25, 2025
A Bright NIR-II Fluorescence Probe for Vascular and Tumor Imaging
Published on: March 17, 2023
Near-Infrared-II Semiconducting Polymer Dots for Deep-tissue Fluorescence Imaging
Nidhi Gupta1,2, Yang-Hsiang Chan3,4, Sampa Saha2
1Department of Applied Chemistry, National Chiao Tung University, Hsinchu, 30010, Taiwan.
Abstract:
Fluorescence imaging, particularly in the NIR-II region (1000-1700 nm), has become an unprecedented tool for deep-tissue in vivo imaging. Among the fluorescent nanoprobes, semiconducting polymer nanoparticles (Pdots) appear to be a promising agent because of their tunable optical and photophysical properties, ultrahigh brightness, minimal autofluorescence, narrow-size distribution, and low cytotoxicity. This review elucidates the recent advances in Pdots for deep-tissue fluorescence imaging and the facing future translation to clinical use.
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