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Antihistamines in asthma.

C Collins-Williams1

  • 1Department of Paediatrics, University of Toronto, Ontario, Canada.

The Journal of Asthma : Official Journal of the Association for the Care of Asthma
|January 1, 1987
PubMed
Summary
This summary is machine-generated.

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Antihistamines are generally safe for most asthma patients, despite concerns about drying respiratory secretions. Many individuals with severe allergic rhinitis benefit from antihistamine use without adverse effects.

Area of Science:

  • Allergy and immunology
  • Pulmonology
  • Pharmacology

Background:

  • Antihistamines have been questioned for asthma use due to potential drying of respiratory secretions.
  • This concern has led to suggestions that antihistamines may be contraindicated in asthma management.

Purpose of the Study:

  • To evaluate the safety and efficacy of antihistamines in patients with asthma.
  • To clarify the relationship between antihistamine use and asthma exacerbations.

Main Methods:

  • Literature review of studies investigating antihistamine effects in asthmatic patients.
  • Analysis of reported adverse reactions and clinical benefits in different asthma subgroups.

Main Results:

  • The consensus indicates antihistamines are not generally contraindicated in asthma.

Related Experiment Videos

  • A small subset of asthmatics may experience chest tightness or wheezing.
  • Most patients with severe perennial allergic rhinitis tolerate antihistamines well and experience significant symptom relief.

    • Conclusions:

    • Antihistamines can be beneficial for managing allergic rhinitis in most asthma patients.
    • Concerns regarding widespread contraindication in asthma appear largely unfounded.
    • Individual patient monitoring is advised for potential, though uncommon, adverse reactions.