Acute disseminated encephalomyelitis after mumps infection in a vaccinated patient
Raquel Gonçalves1, João Gomes2, André Martins1
1Infectious Diseases' Unit, Centro Hospitalar e Universitário de Coimbra, Portugal.
Abstract:
Mumps is an infectious disease caused by a paramyxovirus. It can involve several organs in the acute stage of the infection, including central nervous system. (Rubin et al., 2015) [1] Neurological complications in the post-infectious period are also described, one of which is acute disseminated encephalomyelitis (ADEM). (Jonhson et al., 2004) [2] We present the case of an healthy young man previously vaccinated, who contracted ADEM after mumps.
Insights
Mumps, a viral illness, can lead to neurological issues like acute disseminated encephalomyelitis (ADEM) even after vaccination. This case highlights ADEM as a rare post-infectious complication of mumps in a vaccinated individual.
Area of Science:
- Infectious Diseases
- Neurology
- Virology
Background:
- Mumps is a viral infection caused by a paramyxovirus, known to affect various organs, including the central nervous system.
- Neurological complications, such as acute disseminated encephalomyelitis (ADEM), can occur in the post-infectious phase of mumps.
- Vaccination is a primary preventive measure against mumps, but breakthrough infections and associated complications are possible.
Observation:
- A case study of a previously vaccinated young man is presented.
- The individual contracted ADEM following a mumps infection.
- This highlights a potential neurological sequela despite vaccination.
Findings:
- The study documents a rare instance of ADEM post-mumps.
- It suggests that even vaccinated individuals can be susceptible to certain complications.
- The case underscores the importance of recognizing mumps as a potential trigger for ADEM.
Implications:
- This case contributes to understanding the spectrum of mumps complications.
- It may inform vaccination strategies and post-infectious monitoring.
- Further research into vaccine efficacy against neurological complications is warranted.


