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Treating Fungal Keratitis with Oral Voriconazole Only: A Case Series
Di Chen1, Shaojian Tan1, Wenjin Zou1
1Department of Ophthalmology, Guangxi Medical University First Affiliated Hospital, Nanning, China.
Background:
To report the clinical effect of oral voriconazole only as a treatment for fungal keratitis.
History And Signs:
Three patients (1 female and 2 males) with culture-proven fungal keratitis (1 Mucoraceae, 1 Aspergillus, 1 Fusarium) were included in this study. The patients were treated with oral voriconazole 200 mg twice daily to observe the clinical response in the treatment of fungal keratitis.
Therapy And Outcome:
The mean age of the patients was 51 years and the average treatment duration was 6 weeks. The corneal inflammation in these three patients was eliminated by oral voriconazole only.
Conclusions:
This is the first reported case of oral voriconazole only as a treatment for fungal keratitis. We found that oral voriconazole has a significant clinical effect on the treatment of fungal keratitis.
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