Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Components of immune function studied with lymphoid tumors.

R G Lynch1

  • 1Department of Pathology, University of Iowa College of Medicine, Iowa City 52242.

International Reviews of Immunology
|July 1, 1986
PubMed
Summary

Lymphoid tumors reveal diverse cell phenotypes, aiding research into normal and cancerous lymphoid cells. Understanding tumor plasticity enhances knowledge of cell development and disease mechanisms.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The use of myeloma cells to study immunoregulatory mechanisms.

Immunology today·2014
Same author

A new non-radioactive method for IL-2 bioassay.

Molecules and cells·2000
Same author

Regulatory roles for FcgammaRIII (CD16) and FcgammaRII (CD32) in the development of T- and B-lineage lymphoid cells.

Journal of leukocyte biology·2000
Same author

Characterization of novel FcepsilonRII/CD23 isoforms lacking the transmembrane (TM) segment in human cell lines.

Molecular immunology·2000
Same author

Gammadelta T cell response induced by vaginal Herpes simplex 2 infection.

Immunology letters·1999
Same author

A regulatory role for Fc gamma receptors (CD16 and CD32) in hematopoiesis.

Immunology letters·1999

Area of Science:

  • Immunology
  • Cell Biology
  • Cancer Research

Background:

  • Lymphoid tumors serve as valuable models for studying lymphoid cell biology.
  • These tumors display a range of phenotypes, from resembling normal cells to exhibiting unique characteristics.
  • Phenotypic diversity within lymphoid tumor clones is a common observation, occurring spontaneously or upon stimulation.

Purpose of the Study:

  • To explore the phenotypic spectrum and diversity of lymphoid tumor cells.
  • To investigate the mechanisms driving phenotypic plasticity in lymphoid tumors.
  • To enhance understanding of both normal and malignant lymphoid cell biology.

Main Methods:

  • Analysis of genetic, biochemical, and physiological features of lymphoid tumors.
  • Characterization of phenotypic continuum across related tumor clones.
  • Utilizing advanced laboratory technologies for precise biological analysis.

Main Results:

  • Lymphoid tumors exhibit a broad spectrum of phenotypes, including those not found in normal lymphoid populations.
  • Phenotypic diversity is observed within tumor clones, influenced by various stimuli.
  • Advancements in technology enable detailed analysis of these biological features.

Conclusions:

  • Understanding lymphoid tumor cell plasticity improves knowledge of normal lymphoid cell function.
  • Research into lymphoid tumors provides insights into mechanisms of cell development and malignancy.
  • The study of lymphoid tumors contributes to both fundamental biology and cancer research.

Related Experiment Videos