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Chronic myelomonocytic leukemia terminating as malignant histiocytosis
D C Doll1, T M Grogan, B R Greenberg
1Veterans Administration Medical Center, Phoenix, Arizona 85012.
Hematologic Pathology
|January 1, 1987
Abstract:
A patient with a 3.5 year history of chronic myelomonocytic leukemia who transformed to malignant histiocytosis is reported. The terminal event was characterized by fever, hepatosplenomegaly, thrombocytopenia, and a leukemic blood picture. The pathogenesis of this terminal transformation and proposed future studies are discussed.