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Updated: Nov 24, 2025

Synthesis of Near-Infrared Emitting Gold Nanoclusters for Biological Applications

Synthesis of Near-Infrared Emitting Gold Nanoclusters for Biological Applications

Published on: March 22, 2020

Highly Fluorescent Gold Cluster Assembly.

Hogeun Chang^1,2, Niladri S Karan^1,2, Kwangsoo Shin^1,2

¹Center for Nanoparticle Research, Institute for Basic Science (IBS), Seoul 08826, Republic of Korea.

Journal of the American Chemical Society

|December 21, 2020

Summary

This summary is machine-generated.

Researchers developed highly luminescent gold cluster assemblies (GCA) with up to 90% quantum yield. These novel materials show potential for advanced drug delivery systems.

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Last Updated: Nov 24, 2025

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Published on: April 27, 2018

Area of Science:

Materials Science
Nanotechnology
Photochemistry

Background:

Photoluminescence (PL) in metal nanoclusters (NCs) is limited by low quantum yields (QYs) compared to traditional luminescent materials.
Improving PL efficiency in NCs is crucial for their broader application.

Purpose of the Study:

To synthesize highly luminescent gold cluster assemblies (GCA) with enhanced photoluminescence properties.
To explore the potential of GCA in drug delivery applications.

Main Methods:

Synthesis of Au4(SRCOO-)4 clusters using mercaptocarboxylic acid.
Zn2+-ion-mediated assembly of gold clusters into GCA.
Characterization of GCA's photoluminescence properties and assembly behavior.

Main Results:

Achieved ultrabright greenish-blue fluorescence with a quantum yield (QY) up to 90%.
Demonstrated synergetic effects of aurophilic interactions and metal ion chelation for enhanced luminescence.
Observed tunable dis/reassembly and aggregation-dependent fluorescence in GCA.

Conclusions:

Developed a novel method for synthesizing highly luminescent gold cluster assemblies.
GCA exhibit significant potential for biodegradable and trackable drug delivery systems due to their unique fluorescence properties and assembly behavior.