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Published on: March 30, 2014
HIV- and hypertension-related knowledge and medication adherence in HIV seropositive persons with hypertension
I L Jackson1, J M Okonta2, C V Ukwe2
1Department of Clinical Pharmacy and Biopharmacy, University of Uyo, Uyo 520103, Nigeria.
Insights
People living with HIV and hypertension show better knowledge of hypertension than HIV, but poor adherence to blood pressure medication. This highlights a need for improved management of comorbidities in HIV patients.
Area of Science:
- Medical Science
- Public Health
- Epidemiology
Background:
- Increasing prevalence of age-related diseases like hypertension among people living with HIV (PLWHV).
- Need to assess knowledge, medication adherence, and clinical outcomes in PLWHV with hypertension.
Purpose of the Study:
- To evaluate knowledge of HIV and hypertension among PLWHV.
- To assess adherence to prescribed antiretroviral and antihypertensive medications.
- To determine clinical outcomes, including blood pressure control and viral load, in this population.
Main Methods:
- Utilized Patient's HIV Knowledge Questionnaire (PHKQ), Hypertension Knowledge-Level Scale (HK-LS), and Adherence to Refills and Medication Scale (ARMS).
- Administered questionnaires to 220 eligible patients at a Nigerian hospital's HIV clinic.
- Collected demographic and clinical data, including viral load and blood pressure readings.
Main Results:
- Participants demonstrated higher hypertension knowledge (63.6%) than HIV knowledge (33.3%).
- Adherence to antiretroviral medications (100%) was superior to antihypertensive medications (89.3%).
- Only 56.1% of participants with viral load data had undetectable levels; merely 2.0% achieved controlled blood pressure (<140/90 mmHg).
Conclusions:
- Despite superior hypertension knowledge, adherence to antihypertensive drugs and blood pressure control remain suboptimal.
- Emphasizes the necessity for enhanced HIV education and focused management of comorbidities in people living with HIV.
- Highlights a critical gap in managing hypertension among PLWHV, necessitating targeted interventions.
Background:
There is increasing prevalence of diseases associated with ageing such as hypertension, among people living with HIV (PLWHV). This study sought to assess: (1) knowledge related to HIV infection and hypertension, (2) adherence to prescribed medications and (3) clinical outcomes among HIV-positive persons with hypertension at a Nigerian hospital.
Methods:
The Patient's HIV Knowledge Questionnaire (PHKQ), Hypertension Knowledge-Level Scale (HK-LS) and Adherence to Refills and Medication Scale (ARMS) were administered to 220 eligible patients through the HIV clinic. Demographic and clinical data were also obtained.
Results:
Participants were predominantly females (57.3%), with a median (IQR) age of 46 (38-58) years; majority were married (67.8%) and employed (60.8%). Participants reported a higher hypertension-related knowledge compared with HIV-related knowledge (63.6% versus 33.3%, Z = -10.263, P < 0.001), but better adherence to antiretroviral medications compared to antihypertensives (100.0% versus 89.3%, Z = -9.118, P < 0.001). Of the 98 participants with documented viral load, 55 (56.1%) had undetectable (<40 copies/ml) values; however, only four (2.0%) of the entire sample had controlled (<140/90 mmHg) blood pressure.
Conclusions:
Despite having a higher hypertension-related knowledge, adherence to antihypertensive medications and blood pressure control were poor. There is a need for increased attention to HIV education and comorbidities in PLWHV.
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