[French ccAFU guidelines - update 2020-2022: upper urinary tract urothelial carcinoma]
M Rouprêt1, F Audenet2, M Roumiguié3
1Comité de cancérologie de l'Association française d'urologie, groupe vessie, Maison de l'urologie, 11, rue Viète, 75017 Paris, France; Sorbonne Université, GRC n° 5, Predictive onco-urology, AP-HP, hôpital de la Pitié-Salpêtrière, 83, boulevard de l'Hôpital, 75013 Paris, France.
Summary
Updated French guidelines for upper tract urothelial carcinomas (UTUC) emphasize CT-scan diagnosis and ureteroscopy. Radical nephroureterectomy is standard, but conservative endoscopic treatment and chemotherapy are options for specific UTUC cases.
Area of Science:
- Uro-oncology
- Nephrology
- Oncology
Background:
- Upper tract urothelial carcinomas (UTUC) are rare malignancies.
- Existing French guidelines required updating to reflect current evidence.
Purpose of the Study:
- To propose updated French national guidelines for the diagnosis, treatment, and follow-up of UTUC.
- To provide evidence-based recommendations for urological care.
Main Methods:
- Systematic Medline literature search conducted from 2018 to 2020.
- Evaluation of diagnostic methods, treatment options, and follow-up strategies for UTUC.
- Assessment of evidence levels for various references.
Main Results:
- Diagnosis relies on contrast-enhanced CT scans and ureteroscopy with biopsies.
- Radical nephroureterectomy (RNU) is the standard surgical approach.
- Conservative endoscopic management is feasible for low-risk UTUC (unifocal, low-grade, non-invasive).
- Adjuvant chemotherapy (intravesical post-RNU, systemic for advanced stages) is recommended to reduce recurrence and treat advanced disease.
Conclusions:
- Updated guidelines aim to enhance the quality of urological care for UTUC.
- Standardized diagnostic and treatment protocols will improve patient outcomes.
Keywords:
BassinetCancerCarcinome urothélialCytologie urinaireKidneyReinRenal pelvisSurvieSurvivalUreterUreteroscopyUretèreUrinary cytologyUrothelial carcinomaUrétéroscopieMore Related Videos
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