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Responsive principles and applications of smart materials in biosensing
Zhaoyang Guo1, Haiyang Liu1, Wubin Dai2
1School of Power and Mechanical Engineering & the Institute of Technological Science, Wuhan University, Wuhan, 430072, China.
Smart Materials in Medicine
|December 22, 2020
Summary
Smart materials are revolutionizing biosensing by enabling the detection of biological indicators. This review explores their design, mechanisms, and applications in detecting glucose, nucleic acids, proteins, and enzymes.
Area of Science:
- Analytical Chemistry
- Materials Science
- Biotechnology
Background:
- Biosensing utilizes transducing systems for detecting biological indicators.
- Smart materials respond to stimuli, converting biological signals into quantifiable data.
- Nanomaterials, photonic crystals, and hydrogels are key smart materials in biosensing.
Purpose of the Study:
- To review the integration of smart materials in biosensing systems.
- To discuss the design and responsive mechanisms of these materials.
- To highlight applications in detecting glucose, nucleic acids, proteins, and enzymes.
Main Methods:
- Review of literature on smart materials in biosensing.
- Analysis of material design principles for responsiveness.
- Examination of biosensing mechanisms and signal transduction.
- Categorization of applications based on detected biomolecules.
Main Results:
- Smart materials offer versatile platforms for biosensing applications.
- Responsive mechanisms are tailored for specific biomolecule detection.
- Successful applications demonstrated for glucose, nucleic acids, proteins, and enzymes.
- Identified challenges and future prospects in smart material biosensing.
Conclusions:
- Smart materials are integral to advanced biosensing technologies.
- Further research can overcome current challenges and unlock new applications.
- The field holds significant promise for future diagnostic and analytical tools.
