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Updated: Nov 24, 2025
Efficient Synthesis of All-Carbon Quaternary Centers via the Conjugate Addition of Functionalized Monoorganozinc Bromides
Published on: May 26, 2019
Transition metal catalyzed asymmetric multicomponent reactions of unsaturated compounds using organoboron reagents
Kanak Kanti Das1, Samir Manna, Santanu Panda
1Department of Chemistry, Indian Institute of Technology Kharagpur, Kharagpur 721302, India. spanda@chem.iitkgp.ac.in.
Abstract:
Asymmetric multicomponent reactions allow stitching several functional groups in an enantioselective and atom economical manner. The introduction of boron-based reagents as a multicomponent coupling partner has its own merits. In addition to being non-toxic and highly stable, organoboron compounds can be easily converted to other functional groups in a stereoselective manner. In the last decade several transition metal catalyzed asymmetric multicomponent strategies have been evolved using boron based reagents. This review will discuss the merits and scope of multicomponent strategies based on their difference in the reaction mechanism and transition metals involved.
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