Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Immunodeficiency Diseases

Immunodeficiency Diseases

Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency...

Humoral Immune Responses

Humoral Immune Responses

Development of Immunocompetence

Development of Immunocompetence

The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...

What is the Immune System?

What is the Immune System?

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Emotional and Behavioral Problems in Children and Adolescents With Asthma and Their Association With Disease Severity.

Pediatric pulmonology·2026

Same author

Allergic rhinitis in Latin America: knowledge, attitudes, and clinical practices of specialists in allergy and clinical immunology-CAPRA-SLAAI study.

Allergologia et immunopathologia·2026

Same author

Allergic Rhinitis and Its Impact on Asthma (ARIA)-EAACI Guidelines-2024-2025 Revision: Part II-Guidelines on Oral and Ocular Treatments.

Allergy·2026

Same author

Perinatal tobacco smoke exposure in 12,405 mother-infant pairs: findings from the EISL Phase 3 in South America.

Allergologia et immunopathologia·2026

Same author

Nature prescription for patients with chronic respiratory diseases.

The World Allergy Organization journal·2026

Same author

Associations between modifiable lifestyle behaviors and mental health indicators in adolescents from 48 countries: a cross-sectional study.

BMC pediatrics·2026

Same journal

Cross-cultural adaptation into Brazilian portuguese of an international questionnaire for the assessment of cardiopulmonary resuscitation knowledge among adolescents.

Jornal de pediatria·2026

Same journal

Evaluation of ChatGPT's reliability in answering questions about short stature and growth failure.

Jornal de pediatria·2026

Same journal

Validity of the Khamis-Roche method, relative to bone age, in Portuguese children and adolescents from 11 to 15 years.

Jornal de pediatria·2026

Same journal

Urogenital congenital anomalies in children under 9 years: global disease burden analysis and projections, 1990-2021.

Jornal de pediatria·2026

Same journal

Intraventricular hemorrhage in preterm newborns: a multicenter study in four Brazilian hospitals.

Jornal de pediatria·2026

Same journal

Agreement between Fenton and intergrowth curves in assessing birth weight of preterm infants: Bland-Altman analysis by degree of prematurity and birth weight for gestational age.

Jornal de pediatria·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Nov 24, 2025

Simultaneous Quantification of T-Cell Receptor Excision Circles TRECs and K-Deleting Recombination Excision Circles KRECs by Real-time PCR

Simultaneous Quantification of T-Cell Receptor Excision Circles TRECs and K-Deleting Recombination Excision Circles KRECs by Real-time PCR

Published on: December 6, 2014

Primary immunodeficiencies: a diagnostic challenge?

¹Universidade Federal de São Paulo, Escola Paulista de Medicina, Departamento de Pediatria, Disciplina de Alergia, Imunologia Clínica e Reumatologia,, São Paulo, SP, Brazil.

Jornal De Pediatria

|December 22, 2020

Summary

No abstract available in PubMed .

More Related Videos

A High-Throughput Electrochemiluminescence 7-Plex Assay Simultaneously Screening for Type 1 Diabetes and Multiple Autoimmune Diseases

A High-Throughput Electrochemiluminescence 7-Plex Assay Simultaneously Screening for Type 1 Diabetes and Multiple Autoimmune Diseases

Published on: May 29, 2020

Detection and Enrichment of Rare Antigen-specific B Cells for Analysis of Phenotype and Function

Detection and Enrichment of Rare Antigen-specific B Cells for Analysis of Phenotype and Function

Published on: February 16, 2017

Related Experiment Videos

Last Updated: Nov 24, 2025

Simultaneous Quantification of T-Cell Receptor Excision Circles TRECs and K-Deleting Recombination Excision Circles KRECs by Real-time PCR

Simultaneous Quantification of T-Cell Receptor Excision Circles TRECs and K-Deleting Recombination Excision Circles KRECs by Real-time PCR

Published on: December 6, 2014

A High-Throughput Electrochemiluminescence 7-Plex Assay Simultaneously Screening for Type 1 Diabetes and Multiple Autoimmune Diseases

A High-Throughput Electrochemiluminescence 7-Plex Assay Simultaneously Screening for Type 1 Diabetes and Multiple Autoimmune Diseases

Published on: May 29, 2020

Detection and Enrichment of Rare Antigen-specific B Cells for Analysis of Phenotype and Function

Detection and Enrichment of Rare Antigen-specific B Cells for Analysis of Phenotype and Function

Published on: February 16, 2017