Passiflora incarnata in Neuropsychiatric Disorders-A Systematic Review.

Area of Science:

• Neuroscience
• Pharmacology
• Herbal Medicine

Background:

• Stress, both physical and psychological, can lead to sleep, concentration, and memory issues, as well as affective disorders.
• Passiflora incarnata, commonly known as passionflower, possesses documented therapeutic properties.
• Existing literature suggests passionflower preparations may alleviate stress, insomnia, anxiety, and depression.

Purpose of the Study:

• To systematically review and evaluate the neuropsychiatric effects of Passiflora incarnata.

Main Methods:

• A comprehensive search of PubMed, ClinTrials.gov, and Embase databases was conducted up to October 22, 2019.
• Included studies were randomized clinical trials investigating the effects of Passiflora incarnata on neuropsychiatric disorders.
• Nine clinical trials involving adult participants were included in the systematic review.

Main Results:

• The majority of studies reported a reduction in anxiety levels after administration of Passiflora incarnata preparations.
• The anxiolytic effect was less pronounced in individuals with mild anxiety symptoms.
• No adverse effects, such as memory impairment or psychometric function decline, were reported.

Conclusions:

• Passiflora incarnata shows potential as an adjunctive treatment for certain symptoms in neuropsychiatric patients.
• The herb appears to be safe and well-tolerated, with no significant adverse effects observed.
• Further research may elucidate the full therapeutic scope of Passiflora incarnata in managing neuropsychiatric conditions.