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Related Concept Videos

Waterproofing and Anti-Bacterial Admixtures in Concrete01:22

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Concrete's susceptibility to water absorption is due to the capillary action within the pores of its hydrated cement paste. This action draws water in, creating the need for waterproofing admixtures to prevent such penetration. The efficacy of these admixtures is contingent upon the water pressure, with variations arising from different conditions such as rain, capillary rise, or hydrostatic pressure in structures intended to hold water.
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Superplasticizers are advanced admixtures that enhance the workability of concrete by lowering the water content without compromising the strength of the material. These substances are highly effective water reducers, improving concrete flow, making it easier to work with, and enabling concrete to reach inaccessible areas or densely reinforced sections without mechanical vibration. The key components in superplasticizers are either sulfonated melamine or naphthalene formaldehyde condensates,...
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Accelerating concrete curing is achieved by applying heat and additional moisture. This process accelerates the hydration of the cement, resulting in an earlier strength gain in the concrete. Steam curing is a method wherein the concrete products are either transported through a chamber on a conveyor belt or encased in plastic, allowing steam at atmospheric pressure to circulate freely around them. This process begins with a phase of moist curing that typically lasts between 3 to 5 hours, after...
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Related Experiment Video

Updated: Nov 24, 2025

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A Novel Polyurethane Expandable Root Canal Sealer.

Mohammad Ali Saghiri1, Kasra Karamifar2, Devyani Nath3

  • 1Biomaterial and Prosthodontics Laboratory, Rutgers School of Dental Medicine, Newark, New Jersey; Department of Restorative Dentistry, Rutgers School of Dental Medicine, Newark, New Jersey; Department of Endodontics, University of the Pacific, Arthur A. Dugoni School of Dentistry, San Francisco, California.

Journal of Endodontics
|December 28, 2020
PubMed
Summary
This summary is machine-generated.

A new polyurethane expandable sealer (PES) demonstrated superior biocompatibility and dentinal tubule penetration compared to traditional sealers. This dental material shows promise for improved root canal obturation and long-term sealing efficacy.

Keywords:
Angiogenesis factorbiocompatibility testingcanal sealercytotoxicity testdentinal tubule penetration

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Area of Science:

  • Endodontics
  • Biomaterials Science
  • Dental Research

Background:

  • Root canal sealers are crucial for effective obturation.
  • Evaluating novel materials is essential for advancing endodontic treatment.
  • A new polyurethane expandable sealer (PES) was developed for endodontic applications.

Purpose of the Study:

  • To assess the utility, cytotoxicity, and dimensional changes of a novel polyurethane expandable sealer (PES).
  • To compare the performance of PES against established sealers like AH Plus and Sure-Seal Root.
  • To evaluate the impact of these sealers on angiogenesis and dentinal tubule penetration.

Main Methods:

  • Cytotoxicity was assessed using L929 fibroblasts and an MTS assay.
  • Angiogenesis was evaluated using an advanced choroidal neovascularization model.
  • Root canals of 36 human teeth were obturated with gutta-percha and one of three sealers (AH Plus, Sure-Seal Root, PES) and analyzed via SEM for sealer penetration.

Main Results:

  • The polyurethane expandable sealer (PES) exhibited significantly higher MTS values, indicating good cell viability.
  • PES demonstrated superior penetration depth into dentinal tubules compared to AH Plus and Sure-Seal Root.
  • Angiogenesis markers and dimensional changes favored the PES group, suggesting enhanced biocompatibility.

Conclusions:

  • The polyurethane expandable sealer (PES) shows significant promise for endodontic applications.
  • PES exhibits favorable biocompatibility and excellent adaptation within dentinal tubules.
  • Further research may validate PES as a superior alternative for root canal obturation.