Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Gastric surgery.

H H Stone

    Southern Medical Journal
    |October 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Preoperative cefazolin significantly reduced surgical site infections in gastric surgery patients. Prophylaxis is crucial for high-risk patients, but likely unnecessary for those with gastric hypersecretion due to sterile stomach conditions.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Soft tissue infections.

    The American surgeon·2000
    Same author

    Obstructive jaundice due to Coccidioides immitis.

    Gastrointestinal endoscopy·1996
    Same author

    Surgical Infection Society intra-abdominal infection study. Prospective evaluation of management techniques and outcome.

    Archives of surgery (Chicago, Ill. : 1960)·1993
    Same author

    Acute postoperative hypokalemia.

    Current surgery·1990
    Same author

    Pathogenicity of the enterococcus in surgical infections.

    Annals of surgery·1990
    Same author

    Pancreatic denervation for pain relief in chronic alcohol associated pancreatitis.

    The British journal of surgery·1990
    Same journal

    The Five Essential Concepts of Developmental Medicine: A Medical Paradigm for People with Developmental Disabilities.

    Southern medical journal·2026
    Same journal

    α-Gal Syndrome in the South: Why We Need Treatment Trials, Not Just Tick Prevention.

    Southern medical journal·2026
    Same journal

    Association between Main Pancreatic Duct Size, Comorbidities, and Fistula Formation after Whipple Procedure for Pancreatic Cancer.

    Southern medical journal·2026
    Same journal

    Impact of Temperature Variation on Patients with Acute Severe Asthma.

    Southern medical journal·2026
    Same journal

    Assessing the Accuracy and Reliability of ChatGPT-4 to Answer Clinical EHR Messages in Sports Medicine.

    Southern medical journal·2026
    Same journal

    Diagnostic Utility and Clinical Implications of Inpatient Fecal Occult Blood Testing.

    Southern medical journal·2026
    See all related articles

    Area of Science:

    • Infectious Diseases
    • Surgical Oncology
    • Pharmacology

    Background:

    • Surgical site infections (SSIs) are a significant complication following gastric surgery.
    • Optimizing antibiotic prophylaxis is critical for reducing postoperative complications.
    • Patient-specific factors, like gastric acidity, may influence the efficacy of antibiotic prophylaxis.

    Purpose of the Study:

    • To evaluate the efficacy of cefazolin prophylaxis in reducing surgical site infections in patients undergoing gastric surgery.
    • To determine the impact of preoperative antibiotic timing and bacterial resistance on infection rates.
    • To identify patient populations that may benefit most or least from antibiotic prophylaxis.

    Main Methods:

    • Prospective, double-blind, randomized study design.

    Related Experiment Videos

  • Inclusion of patients undergoing gastric surgery.
  • Administration of parenteral cefazolin before operation.

    • Main Results:

    • Preoperative cefazolin significantly reduced the rate of wound infections.
    • Infections occurred when antibiotic prophylaxis was absent at inoculation or when bacteria were resistant.
    • Patients with gastric hyperacidity benefited from prophylaxis, unlike those with duodenal ulcer disease.

    Conclusions:

    • Preoperative cefazolin is effective in preventing surgical site infections in gastric surgery.
    • Antimicrobial prophylaxis should be administered preoperatively for high-risk patients.
    • Antibiotic prophylaxis may not be indicated for gastric operations in patients with gastric hypersecretion.