Related Experiment Video
Updated: Nov 24, 2025

Pretreatment of Lignocellulosic Biomass with Low-cost Ionic Liquids
Published on: August 10, 2016
One-pot production of lactic acid from rice straw pretreated with ionic liquid
Neerja Yadav1, Lata Nain2, Sunil K Khare1
1Department of Chemistry, Indian Institute of Technology Delhi, India.
Abstract:
Production of platform chemicals has been advocated as a sustainable option to tackle the problems associated with agro-waste management. In this report, for the first time, efforts were made to effectively produce second-generation lactic acid from rice straw pretreated with imidazolium ionic liquid [EMIM][OAc] and subsequently fermented with a promising Lactobacillus plantarum SKL-22 strain saccharified with a commercial cellulase enzyme. Medium optimization was carried out to enhance the lactic acid (LA) yield by response surface methodology. In a 5 L bioreactor, the process was further upscale, and a yield increment of 1.11% was observed. The process using rice straw as substrate led to a LA yield of 36.75 g/L from L. plantarum SKL-22 in a single pot bioprocess. Overall, the above finding has shown the ability of L. plantarum SKL-22 to produce LA from the hydrolysate of rice straw. This study presented a novel environmental-friendly method for LA production.
More Related Videos
Related Concept Videos
Carboxylic Acids to Primary Alcohols: Hydride Reduction
Preparation of Aldehydes and Ketones from Nitriles and Carboxylic Acids
Reducing carboxylic acid derivatives like acyl chlorides (RCOCl), esters (RCO2R′), and nitriles (RCN) using milder aluminum hydride agents like lithium tri-tert-butoxyaluminum hydride [LiAlH(O-t-Bu)3] and diisobutylaluminum hydride [DIBAL-H]...
Acid Halides to Alcohols: LiAlH4 Reduction
The mechanism proceeds in three steps. First, the nucleophilic hydride ion attacks the carbonyl carbon of the acid halide to form a tetrahedral intermediate. Next, the carbonyl group is re-formed, and the halide ion departs as a leaving group, generating an aldehyde. A second nucleophilic attack by the hydride yields an alkoxide ion, which, upon protonation, gives a primary alcohol as...

