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Related Experiment Videos

How common is white coat hypertension?

T G Pickering1, G D James, C Boddie

  • 1Cardiovascular Center, New York Hospital-Cornell University Medical Center, New York, NY 10021.

JAMA
|January 8, 1988
PubMed
Summary

Twenty-one percent of patients with borderline hypertension exhibit "white coat" hypertension, showing normal blood pressure outside the clinic. This phenomenon, more common in younger females, can lead to hypertension misclassification.

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Area of Science:

  • Cardiology
  • Hypertension Research
  • Clinical Medicine

Background:

  • Borderline hypertension affects a significant patient population.
  • Accurate blood pressure monitoring is crucial for diagnosis and treatment.
  • The 'white coat' phenomenon is a known, yet incompletely understood, factor in blood pressure readings.

Purpose of the Study:

  • To identify and characterize patients with "white coat" hypertension among those with untreated borderline hypertension.
  • To determine the prevalence of "white coat" hypertension in this cohort.
  • To explore demographic and clinical factors associated with "white coat" hypertension.

Main Methods:

  • Ambulatory blood pressure monitoring (ABPM) was used to compare clinic readings with daytime pressures.

Related Experiment Videos

  • A cohort of 292 patients with untreated borderline hypertension (90-104 mm Hg diastolic) was studied.
  • Demographic and clinical data were collected and analyzed to identify patient characteristics.

    • Main Results:

    • Twenty-one percent of patients with borderline hypertension had normal daytime ambulatory pressures.
    • "White coat" hypertension was more prevalent in females, younger patients, those with lower weight, and more recent diagnoses.
    • These patients did not exhibit increased blood pressure lability or exaggerated responses at work, suggesting a specific response to the clinical setting.

    Conclusions:

    • "White coat" hypertension is a significant factor in patients with borderline hypertension, potentially leading to misclassification.
    • The pressor response in "white coat" hypertension appears specific to the physician's office environment.
    • Further research is needed to understand the implications and management of "white coat" hypertension.