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Updated: Nov 24, 2025

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
Published on: February 8, 2019
Five-day fever: The main presentation of childhood-onset Takayasu arteritis
Vadood Javadi Parvaneh1, Mohsen Jari2, Khosro Rahmani1
1Department of Pediatric Rheumatology Mofid Children's Hospital Shahid Beheshti University of Medical Sciences Tehran Iran.
Insights
Physicians should consider primary vasculitides in children with prolonged fever and constitutional symptoms, especially if common diseases are ruled out. A history of autoimmunity may indicate this rare condition.
Area of Science:
- Pediatric Rheumatology
- Immunology
Background:
- Nonspecific constitutional symptoms like prolonged fever in children can be challenging to diagnose.
- Common conditions such as infections, malignancies, and other rheumatic disorders are typically considered first.
Abstract:
In children with a nonspecific constitutional presentation such as prolonged fever, the physician should pay attention to primary vasculitides after ruling out the more common diseases such as infectious diseases, malignancies, and the other rheumatic disorders. The past history of autoimmunity may be a clue for this.
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