Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Allergic Reactions02:06

Allergic Reactions

30.2K
Overview
30.2K
Allergic Drug Reactions01:27

Allergic Drug Reactions

1.2K
Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing...
1.2K
Hypersensitivities01:30

Hypersensitivities

4.5K
Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
4.5K
Cross-reactivity00:42

Cross-reactivity

32.1K
Overview
32.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Examining implementation of the first risk stratification-based programme for evaluating penicillin allergy labels in Western Norway hospitals: a study protocol.

BMJ open·2025
Same author

Norwegian Anaesthesiologist's Perspectives on Perioperative Allergies and Penicillin Allergy Evaluations: A National Survey.

Acta anaesthesiologica Scandinavica·2025
Same author

"What if the patient has a severe reaction, and it is my fault?" A qualitative study exploring factors for sustainable implementation of penicillin allergy delabelling.

Antimicrobial resistance and infection control·2024
Same author

Anaphylaxis triggered by alpha-gal allergy.

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke·2024
Same author

Serum mast cell tryptase reference intervals in European populations.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology·2023
Same author

A survey of total IgE reference intervals reported by Scandinavian and British medical laboratories - a need for harmonisation.

Scandinavian journal of clinical and laboratory investigation·2023

Related Experiment Video

Updated: Nov 24, 2025

Antigenic Liposomes for Generation of Disease-specific Antibodies
10:31

Antigenic Liposomes for Generation of Disease-specific Antibodies

Published on: October 25, 2018

12.6K

Anaphylaxis following prick-by-prick testing with peanut.

Marie Alnæs1,2

  • 1Section of Clinical Allergy Department of Occupational Diseases Haukeland University Hospital Bergen Norway.

Clinical Case Reports
|December 28, 2020
PubMed
Summary
This summary is machine-generated.

Anaphylaxis from prick-by-prick testing is rare but serious. Healthcare providers must be prepared to treat it, especially in high-risk patients, using adrenaline and advanced diagnostics.

Keywords:
acute medicineallergy and immunologydermatologyear nose and throat

More Related Videos

Basophil Activation Test for Allergy Diagnosis
07:22

Basophil Activation Test for Allergy Diagnosis

Published on: May 31, 2021

8.9K
Measuring Local Anaphylaxis in Mice
07:49

Measuring Local Anaphylaxis in Mice

Published on: October 14, 2014

19.7K

Related Experiment Videos

Last Updated: Nov 24, 2025

Antigenic Liposomes for Generation of Disease-specific Antibodies
10:31

Antigenic Liposomes for Generation of Disease-specific Antibodies

Published on: October 25, 2018

12.6K
Basophil Activation Test for Allergy Diagnosis
07:22

Basophil Activation Test for Allergy Diagnosis

Published on: May 31, 2021

8.9K
Measuring Local Anaphylaxis in Mice
07:49

Measuring Local Anaphylaxis in Mice

Published on: October 14, 2014

19.7K

Area of Science:

  • Allergy and Immunology
  • Clinical Diagnostics

Background:

  • Prick-by-prick testing is a common diagnostic method for allergies.
  • Anaphylaxis is a severe allergic reaction that can occur during allergy testing.

Observation:

  • Anaphylaxis is a rare but life-threatening complication of prick-by-prick testing.
  • Immediate recognition and treatment of anaphylaxis are crucial.

Findings:

  • Adrenaline (epinephrine) must be readily available for managing anaphylaxis.
  • For high-risk patients with a history of anaphylaxis, component-resolved diagnostics (specific IgE) and basophil activation testing are recommended prior to skin prick testing.

Implications:

  • This highlights the importance of emergency preparedness in allergy testing settings.
  • Pre-testing evaluation with advanced diagnostics can mitigate risks in susceptible individuals.