A rare skin infection in atopic dermatitis: A case report

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Giovanna Malara1, Caterina Trifirò1, Annunziata Bartolotta1

  • 1Dermatology Department Grande Ospedale Metropolitano Bianchi-Melacrino-Morelli Reggio Calabria Italy.

Clinical Case Reports
|December 28, 2020
PubMed

Insights

Atopic dermatitis (AD) patients can develop skin infections from Staphylococcus. This study identified a rare E. faecalis contamination in AD patients linked to excrement exposure.

Area of Science:

  • Dermatology
  • Microbiology
  • Immunology

Background:

  • Atopic dermatitis (AD) is characterized by immune dysregulation, including reduced antimicrobial peptides (AMPs) and Th2 cytokines like IL-17.
  • This immune environment increases susceptibility to bacterial skin infections, commonly by Staphylococcus species.

Observation:

  • This study observed a rare case of Enterococcus faecalis (E. faecalis) skin contamination in patients with atopic dermatitis.
  • The contamination was linked to frequent exposure to animal or human excrement.

Findings:

  • The findings highlight E. faecalis as a potential pathogen in AD skin infections, beyond the typical Staphylococcus.
  • This suggests environmental factors, specifically contact with excrement, can introduce unusual pathogens in immunocompromised AD patients.

Implications:

  • These results broaden the understanding of infectious complications in atopic dermatitis.
  • Clinicians should consider a wider range of bacterial pathogens and environmental exposures when treating AD-associated skin infections.
Keywords:
Enterococcus faecalisStaphylococcus aureusatopic dermatitisskin infection

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