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Recurrent ameloblastoma with both hypercalcemia and BRAF mutation: A case report
Hidenori Suzuki1, Eiichi Sasaki2, Ryota Nakamura3
1Department of Head and Neck Surgery Aichi Cancer Center Hospital Nagoya Japan.
Clinical Case Reports
|December 28, 2020
Summary
This case report details a mandibular ameloblastoma exhibiting both BRAF V600E mutation and hypercalcemia. Surgical intervention with fibula and anterolateral thigh flaps resulted in no recurrence or metastasis at 69 months post-operation.
Area of Science:
- Oral and Maxillofacial Surgery
- Oncology
- Genetics
Background:
- Ameloblastoma is a common odontogenic tumor with a high recurrence rate.
- The BRAF V600E mutation is implicated in ameloblastoma pathogenesis.
- Hypercalcemia is a rare complication associated with ameloblastoma.
