Related Experiment Video

Updated: Nov 24, 2025

Author Spotlight: Advancements in Molecular Biomarker Testing for Non-Squamous Non-Small Cell Lung Cancer
07:59

Author Spotlight: Advancements in Molecular Biomarker Testing for Non-Squamous Non-Small Cell Lung Cancer

Published on: September 8, 2023

1.4K

2019 ASCO Annual Meeting Highlights for the Advanced Practitioner: Non-Small Cell Lung Cancer

    Journal of the Advanced Practitioner in Oncology
    |December 28, 2020
    PubMed

    Insights

    New treatments for non-small cell lung cancer, including checkpoint inhibitors and targeted therapies, offer more options for patients. Advanced practitioners can consider these advancements for improved patient care.

    Area of Science:

    • Oncology
    • Clinical Trials

    Background:

    • Treatment options for non-small cell lung cancer (NSCLC) have evolved.
    • Recent clinical trials have focused on novel therapeutic agents.

    Purpose of the Study:

    • To review key abstracts from the 2019 ASCO Annual Meeting.
    • To discuss the safety and efficacy of emerging therapies for NSCLC.
    • To provide considerations for advanced practitioners managing NSCLC.

    Main Methods:

    • Review of major abstracts presented at the 2019 ASCO Annual Meeting.
    • Analysis of data on checkpoint inhibitors and targeted therapies for NSCLC.
    • Synthesis of information for clinical application.

    Main Results:

    • Checkpoint inhibitors and targeted therapies demonstrate significant safety and efficacy.
    • Expanded treatment options are available for advanced NSCLC.
    • Key findings from the 2019 ASCO Annual Meeting highlight therapeutic progress.

    Conclusions:

    • The landscape of non-small cell lung cancer treatment has been significantly improved by new therapies.
    • Advanced practitioners should integrate findings on checkpoint inhibitors and targeted therapies into clinical practice.
    • Ongoing research continues to expand therapeutic possibilities for NSCLC patients.

    More Related Videos

    Patient-Derived Tumor Explants As a "Live" Preclinical Platform for Predicting Drug Resistance in Patients07:42

    Patient-Derived Tumor Explants As a "Live" Preclinical Platform for Predicting Drug Resistance in Patients

    Published on: February 7, 2021

    5.4K
    Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer04:04

    Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer

    Published on: February 12, 2017

    10.7K

    Related Concept Videos

    Treatment Resistant Cancers02:56

    Treatment Resistant Cancers

    Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
    3.5K
    Targeted Cancer Therapies02:57

    Targeted Cancer Therapies

    The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
    There are several types of targeted therapies against...
    8.1K
    Cancer Therapies02:49

    Cancer Therapies

    Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
    However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
    9.1K
    Tumor Immunotherapy01:27

    Tumor Immunotherapy

    Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
    880
    Adaptive Mechanisms in Cancer Cells02:53

    Adaptive Mechanisms in Cancer Cells

    Cancer cells accumulate genetic changes at an abnormally rapid rate due to the defects in the DNA repair mechanisms. From an evolutionary perspective, such genetic instability is advantageous for cancer development. Mutant cell lines accumulate a series of beneficial mutations that contribute to their progression into cancer.
    Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...
    6.2K
    Cancer Vaccines01:30

    Cancer Vaccines

    Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
    Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
    630