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Related Experiment Videos

Local embolism from vertebral artery occlusion.

M S Pessin1, N Daneault, E S Kwan

  • 1Department of Neurology, Tufts-New England Medical Center, Boston, MA 02111.

Stroke
|January 1, 1988
PubMed
Summary

Vertebral artery occlusion can cause basilar artery stroke through local embolism. This mechanism, though known in other arteries, is underappreciated in the vertebral basilar circulation, potentially worsening outcomes.

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Stroke registries and the vertebro-basilar arterial circulation.

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Area of Science:

  • Neurology
  • Vascular Neurology
  • Cerebrovascular Disease

Background:

  • Stroke in the basilar artery territory can stem from embolism originating at the site of vertebral artery occlusion.
  • This local embolism mechanism is well-documented for the middle cerebral artery territory due to extracranial internal carotid artery disease.
  • However, this mechanism is less appreciated in the vertebral basilar circulation.

Observation:

  • This report details two patients with basilar artery territory infarction.
  • Angiography confirmed the stroke resulted from vertebral artery occlusion and subsequent artery-to-artery embolism.
  • Clinical presentation indicated major infarction in the basilar artery territory.

Findings:

  • Vertebral artery occlusion can lead to artery-to-artery embolism.

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  • This embolism can cause significant basilar artery territory infarction.
  • The stroke mechanism of local embolism is a critical consideration in the vertebral basilar circulation.

    • Implications:

    • Vertebral artery occlusion, often considered benign, can have serious consequences.
    • Recognizing local embolism as a stroke mechanism is crucial for managing vertebral basilar circulation disease.
    • This understanding may alter the perceived prognosis and management strategies for vertebral artery occlusion.