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An Ingestible Electronics for Continuous and Real-Time Intraabdominal Pressure Monitoring
Chien-Hung Liao1, Chi-Tung Cheng1, Chih-Chi Chen2
1Department of Trauma and Emergency Surgery, Linkou Chang Gung Memorial Hospital, Chang Gung University, Taoyuan 333423, Taiwan.
Journal of Personalized Medicine
|December 30, 2020
Summary
This study introduces a novel wireless capsule for gastrointestinal pressure monitoring to detect intraabdominal hypertension (IAH). This technology aims to improve early diagnosis and treatment of abdominal compartment syndrome.
Area of Science:
- Medical Devices
- Gastroenterology
- Critical Care Medicine
Background:
- Abdominal compartment syndrome (ACS) requires timely intervention.
- Current intravesical pressure (IVP) monitoring for intraabdominal hypertension (IAH) can cause treatment delays.
- Accurate and timely IAH detection is crucial for effective ACS management.
Purpose of the Study:
- To present an innovative gastrointestinal intraluminal pressure (GIP) measurement method for monitoring IAH.
- To develop and validate a novel algorithm for detecting IAH using GIP.
- To improve pressure-guided relief of intraabdominal pressure (IAP).
Main Methods:
- Development of a wireless, ingestible pressure-sensing capsule (10 × 13 mm) for absolute GIP measurement.
- Implementation of a novel algorithm for IAH detection in a live porcine model.
- Estimation of IAP during artificial pneumoperitoneum using pressure waveform analysis.
Main Results:
- The wireless pressure sensor successfully estimated IAP.
- Pressure waveform-based measurements indicated predictive capability for IAP.
- The developed algorithm demonstrated effectiveness in detecting IAH in a porcine model.
Conclusions:
- A continuous, ingestible wireless electronics-based pressure waveform measurement device can enhance GIP monitoring for predicting IAH.
- This technology can complement existing IAH monitoring modalities.
- The proposed system offers valuable data for digital health platforms in critical care settings.
