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The lateral distribution of cholesterol in the plane of lipid multibilayers
1Centre for Mathematical Simulation, St. Francis Xavier University, Antigonish, Nova Scotia, Canada.
Biochimica Et Biophysica Acta
|January 22, 1988
Abstract:
We consider three models of cholesterol distribution in the plane of a bilayer of DMPC. We analyse recent 2H-NMR data obtained from deuterated fluorescent probes and show that, on the characteristic time-scale of 2H-NMR, it is in accord with a random distribution of cholesterol in a fluid-like DMPC bilayer in a single phase at least for T greater than or approximately equal to 35 degrees C and for 0 less than or equal to c less than or equal to 0.42.