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Related Concept Videos

Cardiac Catheterization I: Pre-Procedure Overview01:28

Cardiac Catheterization I: Pre-Procedure Overview

542
Cardiac catheterization is an invasive diagnostic technique used to identify and evaluate structural and functional diseases of the heart and major blood vessels. This technique diagnoses congenital heart disease, coronary artery disease, valvular heart disease, and coronary spasms and assesses ventricular function. It helps guide treatment decisions, including the need for revascularization procedures like percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) and...
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Cardiac Catheterization II: Right Heart Catheterization01:21

Cardiac Catheterization II: Right Heart Catheterization

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Right Heart Catheterization: An OverviewRight heart catheterization is an invasive diagnostic procedure that measures right-sided cardiac and pulmonary artery pressures, calculates cardiac output, and identifies intracardiac shunts. It provides detailed hemodynamic data essential for diagnosing and managing various cardiovascular conditions, such as pulmonary hypertension.Access SitesCommon access sites for right heart catheterization include the internal jugular vein in the neck region, the...
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Cardiac Catheterization III: Left Heart Catheterization01:24

Cardiac Catheterization III: Left Heart Catheterization

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Left heart catheterization is an invasive diagnostic procedure used to evaluate the function and structure of the left side of the heart. It is generally performed to diagnose and treat cardiovascular conditions such as valve abnormalities, coronary artery disease, and congenital heart defects.Diagnostic and therapeutic purposesLeft heart catheterization serves various diagnostic and therapeutic purposes, including:Assessing coronary artery bypass grafts.Evaluating coronary artery disease in...
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Cardiac Catheterization IV: Nursing Management01:26

Cardiac Catheterization IV: Nursing Management

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Nursing responsibilities before cardiac catheterization include:Assess for allergies and establish baseline health status.Before cardiac catheterization, assess the patient for allergies to contrast dye. Perform a comprehensive baseline assessment, including vital signs, heart and breath sounds, and a neurovascular assessment of the extremities, noting distal pulses, skin color, and temperature. Instruct the patient to fast for 8-12 hours before the procedure. Evaluate baseline laboratory...
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Updated: Nov 23, 2025

Novel Percutaneous Approach for Deployment of 3D Printed Coronary Stenosis Implants in Swine Models of Ischemic Heart Disease
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A Next-Generation Guide Extension System for Percutaneous Coronary Intervention.

Tim A Fischell1, Jeffrey Payne2, Kimberly Wehde2

  • 1CrossLiner, Inc., Kalamazoo, MI, United States of America.

Cardiovascular Revascularization Medicine : Including Molecular Interventions
|December 31, 2020
PubMed
Summary
This summary is machine-generated.

The new CrossLiner™ guide extension system safely achieved deeper coronary intubation compared to first-generation devices in a porcine model. This advancement in percutaneous coronary intervention (PCI) shows promise for improved procedural outcomes.

Keywords:
Catheter designCoronary artery diseaseGuide extensionStents

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Area of Science:

  • Cardiovascular Interventions
  • Medical Device Technology
  • Preclinical Research

Background:

  • Guide catheter extensions are crucial for percutaneous coronary intervention (PCI).
  • First-generation devices have limitations in deep coronary intubation.
  • The CrossLiner™ represents a next-generation system designed for safer, deeper access.

Purpose of the Study:

  • To evaluate the efficacy of the CrossLiner™ guide extension system.
  • To compare its performance against first-generation devices (GuideLiner™, GuideZilla™).
  • To assess deep coronary intubation capabilities in a preclinical model.

Main Methods:

  • A head-to-head study was conducted in a porcine coronary model.
  • The CrossLiner™ was tested against existing guide extensions during stenting procedures.
  • Data collected focused on the ability to achieve deep vessel intubation.

Main Results:

  • The CrossLiner™ successfully intubated 8/8 vessels, crossing distal stented segments.
  • First-generation devices showed limited success, often getting stuck proximal or at stent edges (p < 0.0002).
  • Average intubation depth was significantly greater with CrossLiner™ (12.9 cm) vs. first-generation (5.6 cm) (p < 0.001).

Conclusions:

  • The CrossLiner™ system demonstrates superior performance for deep coronary intubation.
  • It offers potential advantages over current first-generation guide extension devices.
  • Further clinical studies are needed to confirm its role in PCI.