Early Clinical Experience With CrossFAST, a Novel, Microcatheter-Led Delivery System for Complex Percutaneous...

Area of Science:

• Cardiovascular Interventions
• Medical Device Technology

Background:

• Guide extension catheters are crucial in coronary intervention but have limitations.
• First-generation devices are monorail, blunt-ended tubular structures.
• CrossFAST (Vantis Vascular) is a novel microcatheter-led system for deep coronary intubation.

Purpose of the Study:

• To describe the CrossFAST device delivery system.
• To review early clinical cases using CrossFAST for complex percutaneous coronary intervention.

Main Methods:

• The CrossFAST system received FDA 510(k) clearance in December 2024.
• Four complex percutaneous coronary intervention cases utilizing CrossFAST were reviewed.

Main Results:

• CrossFAST successfully assisted in-stent delivery in all four cases.
• The device navigated target lesions, enabling seamless stent placement.
• Complications were avoided, even after conventional methods failed.

Conclusions:

• CrossFAST proved effective in complex, calcific coronary artery disease cases.
• The system aided coronary device delivery and placement.
• Further research is needed to compare CrossFAST safety and efficacy against conventional approaches.