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Traditional Chinese Medicine for Essential Hypertension: A Clinical Evidence Map
Yan Zhang1,2,3, Biqing Wang4,2,3, Chunxiao Ju4,2,3
1Graduate School of China Academy of Chinese Medical Sciences, Beijing 100700, China.
Evidence-Based Complementary and Alternative Medicine : Ecam
|December 31, 2020
Summary
Traditional Chinese Medicine (TCM) shows potential for managing essential hypertension (EH), particularly in the elderly. However, current evidence quality necessitates further high-quality, standardized research for definitive conclusions.
Area of Science:
- Integrative Medicine
- Cardiovascular Health
- Evidence-Based Practice
Background:
- Essential hypertension (EH) is a global health concern requiring diverse therapeutic strategies.
- Traditional Chinese Medicine (TCM) has a long history in managing various health conditions, including hypertension.
- An evidence map approach is valuable for understanding the landscape of TCM research for EH.
Purpose of the Study:
- To systematically map and summarize clinical evidence on TCM for essential hypertension (EH) prevention and treatment.
- To identify research gaps and prioritize future research directions in TCM for EH.
- To assess the quality and trends of published TCM research on EH.
Main Methods:
- Systematic retrieval and synthesis of clinical studies, systematic reviews, and guidelines on TCM for EH (2000-2019).
- Inclusion of studies from multiple databases (CNKI, WanFang Data, VIP, PubMed, Embase, Web of Science).
- Analysis of evidence distribution, intervention characteristics, and review quality (AMSTAR scores).
Main Results:
- A total of 9,403 articles were included, with a rising publication trend over time.
- Chinese herbal medicine (CHM) interventions, typically 4-8 weeks, were common for elderly hypertension.
- Systematic reviews (SRs) indicated potential benefits of TCM in lowering blood pressure and improving outcomes, though often supported by low-quality evidence.
Conclusions:
- TCM, particularly CHM, shows potential benefits for essential hypertension, especially in the elderly.
- Evidence suggests TCM can lower blood pressure, improve symptom scores, and increase total effective rates.
- Significant limitations in the quality and standardization of primary studies necessitate further rigorous research to confirm TCM's efficacy and safety in EH management.
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