Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

14.9K
Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
14.9K
Autism Spectrum Disorder01:19

Autism Spectrum Disorder

701
Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
701
Genomics02:02

Genomics

38.9K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
38.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Analytical Validation of an ELISA Assay for Maternal Autoantibody-Related Autism.

Diagnostics (Basel, Switzerland)·2026
Same author

Welfare Assessment in Equine-Assisted Service (EAS) Horses.

Animals : an open access journal from MDPI·2026
Same author

De Novo Variants Predominate in Autism Spectrum Disorder.

Genes·2025
Same author

A Mitochondrial Supplement Improves Function and Mitochondrial Activity in Autism: A Double-Blind Placebo-Controlled Cross-Over Trial.

International journal of molecular sciences·2025
Same author

ONT in Clinical Diagnostics of Repeat Expansion Disorders: Detection and Reporting Challenges.

International journal of molecular sciences·2025
Same author

Understanding the Patient Experience with Twice-Nightly Sodium Oxybate Therapy for Narcolepsy: A Social Listening Experiment.

Brain sciences·2025

Related Experiment Video

Updated: Nov 23, 2025

Author Spotlight: Exploring Autism Spectrum Disorder Symptoms in Fruit Flies — Genetic Models and Behavioral Tests
08:30

Author Spotlight: Exploring Autism Spectrum Disorder Symptoms in Fruit Flies — Genetic Models and Behavioral Tests

Published on: September 6, 2024

2.2K

The Temple Grandin Genome: Comprehensive Analysis in a Scientist with High-Functioning Autism.

Rena J Vanzo1, Aparna Prasad1, Lauren Staunch1

  • 1Lineagen, Inc., Salt Lake City, UT 84109, USA.

Journal of Personalized Medicine
|January 1, 2021
PubMed
Summary
This summary is machine-generated.

Genomic analysis of Temple Grandin identified genetic variants in SHANK2, ALX1, and RELN associated with autism spectrum disorder (ASD). Additional variants may explain other clinical features, highlighting the complexity of ASD genetics.

Area of Science:

  • Genetics
  • Neurodevelopmental Disorders
  • Personalized Medicine

Background:

  • Autism spectrum disorder (ASD) presents a complex genetic basis, influencing phenotype and clinical features.
Keywords:
Temple Grandinautism spectrum disorderchromosomal microarray analysisclinical utilitygenetic testingpolygenic risk scoreswhole exome sequencingwhole genome sequencing

More Related Videos

A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia
05:51

A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia

Published on: June 15, 2011

26.2K
Strategies for Assessing Autistic-Like Behaviors in Mice
07:38

Strategies for Assessing Autistic-Like Behaviors in Mice

Published on: September 20, 2024

1.8K

Related Experiment Videos

Last Updated: Nov 23, 2025

Author Spotlight: Exploring Autism Spectrum Disorder Symptoms in Fruit Flies — Genetic Models and Behavioral Tests
08:30

Author Spotlight: Exploring Autism Spectrum Disorder Symptoms in Fruit Flies — Genetic Models and Behavioral Tests

Published on: September 6, 2024

2.2K
A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia
05:51

A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia

Published on: June 15, 2011

26.2K
Strategies for Assessing Autistic-Like Behaviors in Mice
07:38

Strategies for Assessing Autistic-Like Behaviors in Mice

Published on: September 20, 2024

1.8K
  • Understanding the genetic underpinnings of ASD is crucial for medical management, personalized treatments, and identifying associated health risks.