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Updated: Nov 23, 2025

A Model of Long-Term Ventricular Fibrillation in Isolated Rat Hearts
Published on: February 17, 2023
Torsades de Pointes and Prolonged Self-Terminating Ventricular Fibrillation Induced by Amiodarone
Georgios D Tziatzios1, Matthaios Didagelos1, Ioannis Tziatzios1
1Cardiology, AHEPA Hospital, Aristotle University of Thessaloniki, Thessaloniki, GRC.
Abstract:
A 71-year-old man with a recent diagnosis of pneumonia developed paroxysmal atrial fibrillation and was admitted to the cardiology service. Amiodarone was administered intravenously to restore sinus rhythm. Significant prolongation of the QT interval (QTc = 640ms) was noted and an exceedingly prolonged (over 3 minutes), self-terminating, episode of ventricular flutter/fibrillation occurred during bedside monitoring. The event was terminated without first converting to a more organized ventricular rhythm and without any adverse neurological sequelae. Apart from the long duration of ventricular fibrillation and its spontaneous termination, our case highlights the importance of the continuous heart rhythm monitoring in patients with extreme QT interval prolongation.
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