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MULTI-MODAL IMAGING IN DIFFUSE SUBRETINAL FIBROSIS WITH UVEITIS SYNDROME.
Aina Moll-Udina1,2, Carmen Alba-Linero1, Victor Llorenç1,2
1Hospital Clínic de Barcelona, Instituto de Oftalmología, Facultad de Medicina, Universidad de Barcelona, Barcelona, Spain; and.
Retinal Cases & Brief Reports
|January 4, 2021
Summary
This study details a rare case of diffuse subretinal fibrosis and uveitis syndrome, highlighting multimodal imaging findings. Advanced imaging techniques like En-face OCT-A aid in monitoring disease activity and chronic changes.
Area of Science:
- Ophthalmology
- Medical Imaging
Background:
- Diffuse subretinal fibrosis and uveitis syndrome is a rare condition.
- Posterior uveitis can lead to significant vision loss.
Observation:
- A young patient presented with severe bilateral vision loss due to posterior uveitis unresponsive to corticosteroids.
- Multimodal imaging, including ultra-widefield imaging, OCT-A, and en-face OCT-A, was utilized to assess the condition.
Findings:
- Bilateral foveal fibrosis plaques and multifocal choroidal lesions were observed.
- Ultra-widefield autofluorescence showed hyperfluorescent patterns indicating disease activity.
- En-face OCT-A revealed hyperreflective lesions and fibrosis plaques, while OCT-A showed neovascularization.
Implications:
- This case is the first to report comprehensive en-face OCT-A and OCT-A findings in diffuse subretinal fibrosis and uveitis syndrome.
- Multimodal imaging enhances the monitoring of disease activity and chronicity.
- Intravitreal dexamethasone implants and anti-TNFα therapy were necessary for disease control.
