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Updated: Nov 23, 2025

Intracoronary Acetylcholine Provocation Testing for Assessment of Coronary Vasomotor Disorders
Published on: August 18, 2016
[The elderly patient with acute coronary syndrome]
Insights
Elderly patients with acute coronary syndrome (ACS) are undertreated. Guideline-adherent therapy, particularly interventional revascularisation, significantly benefits older individuals.
Area of Science:
- Cardiology
- Geriatric Medicine
- Interventional Cardiology
Background:
- Acute coronary syndrome (ACS) management in elderly patients is often suboptimal.
- Age, comorbidities, and bleeding risk influence treatment decisions, leading to deviations from evidence-based guidelines.
Observation:
- Elderly patients with ACS present unique challenges in treatment selection.
- Both pharmacological and interventional therapies are frequently underutilized in this demographic.
Findings:
- Despite concerns, elderly patients demonstrate significant benefit from guideline-adherent ACS therapy.
- Interventional revascularisation shows particular efficacy in improving outcomes for older adults with ACS.
Implications:
- Clinical practice should prioritize guideline-based treatment for elderly ACS patients.
- Interventional revascularisation should be considered more frequently in elderly patients with ACS.
- Further research may explore tailored strategies to mitigate risks and optimize benefits in this population.
Abstract:
The elderly patient with acute coronary syndrome (ACS) is often not treated on an evidence based basis due to age, previous illnesses and also an increased risk of bleeding. This applies to both drug and interventional therapy. However, valid data clearly show that elderly patients in particular benefit from guideline-adherent therapy, especially interventional revascularisation.
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