Level of Serum Vitamin D, To Which People Are at Risk of Developing Acute Myocardial Infarction in Bangladesh

K Akter1, I Khalilullah, S N Saqueeb

  • 1Dr Khaleda Akter, Specialist, Laboratory Diagnostic Services, Ibrahim Cardiac Hospital & Research Institute (ICH&RI), Dhaka, Bangladesh;

Insights

Low vitamin D levels are linked to a higher risk of myocardial infarction (MI). This study found significantly lower serum vitamin D in patients with ST-elevation myocardial infarction (STEMI) and non-ST-elevation myocardial infarction (NSTEMI) compared to controls.

Area of Science:

  • Cardiology
  • Endocrinology
  • Public Health

Background:

  • Myocardial infarction (MI) incidence is rising in developing nations, often linked to coronary atherosclerosis.
  • Vitamin D deficiency is increasingly recognized as a potential risk factor for atherosclerosis development.

Purpose of the Study:

  • To investigate the association between serum vitamin D levels and acute myocardial infarction.
  • To determine if vitamin D deficiency is an independent risk factor for MI.

Main Methods:

  • A case-control study design was employed.
  • Subjects were divided into three groups: STEMI, NSTEMI, and a control group of individuals without acute MI.
  • Serum vitamin D levels were measured and compared across the groups.

Main Results:

  • Mean serum vitamin D levels were significantly lower in STEMI (20.17 ng/ml) and NSTEMI (20.8 ng/ml) groups compared to the control group (24.77 ng/ml) (p<0.001).
  • A statistically significant difference in vitamin D levels was observed among the three groups (p<0.001).
  • Individuals with serum vitamin D <20 ng/ml demonstrated a higher likelihood of developing acute MI.

Conclusions:

  • Low serum vitamin D is an independent risk factor for acute myocardial infarction.
  • Maintaining adequate vitamin D levels may be crucial for preventing MI, particularly in at-risk populations.

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