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Updated: Nov 23, 2025

Laparoscopic Repair of Para-Esophageal Hernia Using Absorbable Biosynthetic Mesh
Published on: September 11, 2021
Paraesophageal hernia repair can decrease BNP levels.
Shunsuke Tanabe1, Yasuhiro Shirakawa2,3, Naoaki Maeda1
1Department of Gastroenterological Surgery, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
Giant paraesophageal hernia (PEH) can cause heart failure symptoms. Laparoscopic surgery significantly reduced heart failure markers and improved symptoms in patients with giant PEH.
Area of Science:
- Gastroenterology
- Cardiology
- Thoracic Surgery
Background:
- Giant paraesophageal hernia (PEH) can lead to gastric torsion, respiratory distress, and heart failure symptoms.
- Patients with significant cardiac load from giant PEH experience reduced quality of life.
Purpose of the Study:
- To examine changes in heart failure markers and symptoms in giant PEH patients before and after laparoscopic surgery.
- To evaluate the impact of surgery on cardiac function in individuals with giant PEH.
Main Methods:
- Brain natriuretic peptide (BNP) levels, a heart failure marker, were measured pre- and post-surgery in patients with giant PEH (types III and IV).
- Symptomatic changes related to heart failure were assessed following radical laparoscopic surgery.
Main Results:
- Of 50 giant PEH cases, 20 (40%) presented with heart failure symptoms.
- Postoperative BNP levels decreased in 18 of 23 evaluated giant PEH cases, indicating improved heart function.
- Chest symptoms commonly improved after surgery.
Conclusions:
- Radical laparoscopic surgery is effective in mitigating heart failure caused by giant PEH.
- Increased cardiac load could be considered a new criterion for surgical intervention in giant PEH cases, alongside traditional indications.
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