Related Experiment Video
Updated: Nov 23, 2025

Activation and Conjugation of Soluble Polysaccharides using 1-Cyano-4-Dimethylaminopyridine Tetrafluoroborate CDAP
Published on: June 14, 2021
Photo-Controllable Catalysis and Chiral Monosaccharide Recognition Induced by Cyclodextrin Derivatives
Lei Chen1, Yong Chen1, Yi Zhang1
1College of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin, 300071, P. R. China.
Abstract:
A supramolecular catalytic system was constructed from polycationic α-cyclodextrin (6-Iz-α-CD) and gold nanoparticles (AuNP) using a supramolecular assembly strategy. The cavity of cyclodextrin is the channel by which the substrate molecules come into contact with the catalytic center. Introduction of the azobenzene-modified diphenylalanine (Azo-FF) guest molecule allowed for precise photo-control of the catalytic activity owing to its sensitive response to irradiation. Importantly, as a unique glucose oxidase the AuNP@6-Iz-α-CD realizes unprecedented chiral recognition catalysis for chiral monosaccharides. In combination with a 3,3',5,5'-tetramethylbenzidine (TMB) color reaction, AuNP@6-Iz-α-CD is able to recognize the chirality of various monosaccharides.
Related Concept Videos
Prochirality
Photochemical Electrocyclic Reactions: Stereochemistry
Selection Rules: Photochemical Activation
Regioselectivity and Stereochemistry of Acid-Catalyzed Hydration
Thermal and Photochemical Electrocyclic Reactions: Overview
Cycloaddition Reactions: MO Requirements for Photochemical Activation
Cycloaddition Reactions: Overview

