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Updated: Nov 22, 2025

Enrichment of Mammalian Tissues and Xenopus Oocytes with Cholesterol
Published on: March 25, 2020
Cholesterol: Bioactivities, Structural Modification, Mechanisms of Action, and Structure-Activity Relationships
Kong Zhang1, Tianze Li1, Xijie Shan1
1College of Plant Protection, Northwest A&F University, Yangling 712100, Shaanxi Province, China.
Abstract:
Cholesterol, steroid alcohol, was discovered by M.E. Chevreul in 1815. Cholesterol and its derivatives showed a large variety of biological properties such as anticancer activity, anticardiac activity, anti-inflammatory activity, antimicrobial activity, anti-psychotic activity, antioxidant activity, drug-loaded activity, etc. In this mini-review, the advances of structural modification of cholesterol from 2014 to 2020 are summarized. In addition, the bioactivities, mechanisms of action and structureactivity relationships of cholesterol and its related derivatives are also discussed.
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