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Related Experiment Video

Updated: Nov 22, 2025

Prospective, Randomized, and Controlled Study of a Human Umbilical Cord Mesenchymal Stem Cell Injection for Treating Diabetic Foot Ulcers
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Diabetic Foot Management: How Could a Procedural Pathway Improve the Surgical Outcome?

V Belgaid1, C Courtin1, R Desmarchelier1

  • 1Department of Orthopaedic and Traumatology, Centre Hospitalier Lyon-Sud, Pierre-Benite, France.

Malaysian Orthopaedic Journal
|January 6, 2021
PubMed
Summary

Implementing a new diabetic foot management pathway reduced revision surgeries by 25%. This simple, cost-effective approach improves outcomes for diabetic foot patients, though more research is needed.

Keywords:
amputationdiabetesfootorthopaedic surgerypathway

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Area of Science:

  • Podiatry
  • Orthopaedic Surgery
  • Public Health

Background:

  • Diabetic foot ulcers are a leading cause of non-traumatic amputations, posing a significant public health challenge.
  • Multidisciplinary management improves surgical outcomes for diabetic foot pathology.
  • Limited data exist on tools to support multidisciplinary diabetic foot care.

Purpose of the Study:

  • To evaluate if a specific diabetic foot management pathway improves treatment outcomes.
  • To assess the impact of a structured pathway on diabetic foot care.

Main Methods:

  • A cross-sectional study comparing retrospective (pre-pathway) and prospective (post-pathway) patient groups.
  • 51 patients with diabetic foot referred for surgical opinion were included.
  • Treatment outcomes were compared between groups treated with the previous method and the new pathway.

Main Results:

  • Amputation rates were similar: 74% (retrospective) vs. 73% (prospective).
  • Revision surgery rates significantly decreased from 39% in the retrospective group to 14% in the prospective group (p=0.05).

Conclusions:

  • The implemented diabetic foot pathway is simple, cost-effective, and recommended for guiding interdisciplinary management.
  • Further prospective studies with larger cohorts are warranted for a comprehensive understanding of the pathway's benefits.