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Optimal Experimental Design for Systems and Synthetic Biology Using AMIGO2

Eva Balsa-Canto1, Lucia Bandiera2,3, Filippo Menolascina2,3

  • 1(Bio)Process Engineering Group, IIM-CSIC (Spanish National Research Council), Vigo, Spain. ebalsa@iim.csic.es.

Methods in Molecular Biology (Clifton, N.J.)
|January 6, 2021
PubMed
Summary

Dynamic modeling in systems biology faces challenges with nonlinear models and unknown parameters. Optimal experimental design (OED) using the AMIGO2 toolbox helps select experiments to improve model identification and parameter estimation.

Keywords:
Biological systemsDynamic modelsOptimal experimental designPractical identifiability

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