User-centred assistive SystEm for arm Functions in neUromuscuLar subjects (USEFUL): a randomized controlled study

Area of Science:

• Rehabilitation Engineering
• Assistive Technology
• Neuromuscular Disorders

Background:

• Upper limb assistive devices help compensate for muscle weakness and aid daily activities.
• A scientific comparison of the efficacy of various upper limb assistive devices is lacking.

Purpose of the Study:

• To compare the functional improvement in upper limb function for patients with muscular dystrophy using two different arm support devices.
• To assess the effectiveness and usability of a passive versus a semi-active assistive device.

Main Methods:

• A multi-centric randomized controlled trial with a cross-over design was conducted.
• 36 patients with muscular dystrophy tested a passive device (Wrex) and a semi-active device (Armon Ayura).
• Functional outcomes were evaluated using the Performance of the Upper Limb (PUL) module, Abilhand questionnaire, and System Usability Scale (SUS).

Main Results:

• Most patients showed improved upper limb function with arm supports.
• Effectiveness varied by impairment level; semi-active devices provided greater benefits for moderate to severely impaired patients (PUL increase of 9-12 points).
• Passive devices had limitations for severely impaired individuals due to strength requirements; usability was rated 'good' (passive) to 'excellent' (semi-active).

Conclusions:

• Assistive devices can enhance the quality of life for individuals with muscular dystrophy.
• Semi-active devices with an additional active degree of freedom improve efficacy and usability, particularly for moderate to severe cases.
• Further research is needed to establish long-term effects on quality of life and disease progression.