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Updated: Nov 22, 2025

Author Spotlight: Development and Evaluation of a Compound Acne Rodent Model Using C. acnes and Oleic Acid
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Rhinophyma in women: a case series.

D Ismail1, L Asfour2, V Madan2

  • 1Laser Division, Department of Dermatology, Salford Royal NHS Foundation Trust, Salford, M6 8HD, UK. dina.ismail@srft.nhs.uk.

Lasers in Medical Science
|January 7, 2021
PubMed
Summary
This summary is machine-generated.

Rhinophyma, rare in women, can significantly impact quality of life. Fractional or fully ablative carbon dioxide (CO2) laser, with or without oral isotretinoin, offers effective treatment for female rhinophyma patients.

Keywords:
CO2FemalesLasersRhinophymaRosacea

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Area of Science:

  • Dermatology
  • Laser Therapy
  • Cosmetic Surgery

Background:

  • Rosacea predominantly affects females, but rhinophyma, an advanced form, is rare in this demographic.
  • Rhinophyma can severely impact a patient's quality of life.
  • Various treatments exist, but effectiveness varies.

Purpose of the Study:

  • To review the presentation, treatment, and outcomes of rhinophyma in female patients.
  • To evaluate the efficacy of carbon dioxide (CO2) laser therapy and oral isotretinoin for female rhinophyma.

Main Methods:

  • Retrospective case review of 7 female patients with rhinophyma.
  • Assessment of presentation, treatments (fractional CO2 laser, fully ablative CO2 laser, oral isotretinoin), and outcomes.
  • Data collected from a tertiary NHS laser centre and a private dermatology clinic.

Main Results:

  • Patients presented at a mean age of 47, with some developing symptoms before 30.
  • Four patients achieved good cosmetic outcomes with fractional CO2 laser.
  • Two patients experienced scarring after fully ablative CO2 laser; long-term low-dose oral isotretinoin was used for relapse prevention in three patients.

Conclusions:

  • Female patients with rhinophyma may present at an earlier age and stage.
  • Fractional or fully ablative CO2 laser, alone or combined with oral isotretinoin, is a highly effective treatment for female rhinophyma.
  • Early intervention and tailored treatment strategies are crucial for optimal outcomes.