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Complete Genome Sequence of Streptococcus mitis Strain Nm-65, Isolated from a Patient with Kawasaki Disease
Atsushi Tabata1, Hisashi Ohkuni2, Yasuhiko Itoh3
1Department of Bioscience and Bioindustry, Graduate School of Technology, Industrial and Social Sciences, Tokushima University, Tokushima, Tokushima, Japan.
Abstract:
Streptococcus mitis Nm-65 is a human commensal streptococcal strain of the mitis group that was isolated from the tooth surface of a patient with Kawasaki disease. The complete genome sequence of Nm-65 was obtained by means of hybrid assembly, using two next-generation sequencing data sets. The final assembly size was 2,085,837 bp, with 2,039 coding sequences.
Insights
The complete genome of Streptococcus mitis Nm-65, a strain linked to Kawasaki disease, was sequenced. This provides a foundation for understanding its role in human health and disease.
Area of Science:
- Microbiology
- Genomics
- Human commensal bacteria
Background:
- Streptococcus mitis is a human commensal bacterium.
- Kawasaki disease is an inflammatory condition affecting young children.
- The specific strain Nm-65 was isolated from a patient with Kawasaki disease.
Purpose of the Study:
- To obtain the complete genome sequence of Streptococcus mitis Nm-65.
- To provide a genomic resource for studying this strain.
Main Methods:
- Hybrid assembly of sequencing data.
- Utilized two next-generation sequencing data sets.
Main Results:
- The complete genome sequence of Nm-65 was successfully assembled.
- The final assembly size is 2,085,837 base pairs.
- The genome contains 2,039 predicted coding sequences.
Conclusions:
- The genome sequence of Streptococcus mitis Nm-65 is now available.
- This genomic data can facilitate future research into the bacterium's biology and its potential association with Kawasaki disease.
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